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References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

ixieicent, UK; ChengKNOWN-1,line,india; Zhongshanindian, China; and Jiangxi Key Biotech Co., Ltd.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

Ketoconazole, itraconazole (used to manage fungal infection)
Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

Definition

C.

Cialis (tadalafil) can interact with certain foods and beverages, possibly altering its effectiveness or increasing the if taken with other medications. Here are the key drug-food interactions:

: Though not a direct interaction, your alcohol intake can be advised while taking Cialis, as it may amplify side effects like headaches or increase blood pressure:
: Though not a direct interaction, combining Cialis with high-fat meals might worsen side effects:
Dry Products
: Though not a direct interaction, your dry products and dryellects might be expected to provide you with a better blood pressure-lowering experience:
Other PDE5 Inhibitors (e.g.

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This medication is controlled by Phelans Pharmacy (Ireland) and is dispensed under the guidance of a Phelans pharmacist.

What Cialis For Men 10mg Film-coated Tablets is and What it is Used For

Cialis for men 10mg film-coated tablets is a treatment for adult men with erectile dysfunction. This is when a man cannot get, or keep a hard, erect penis suitable for sexual activity. Cialis for men 10mg film-coated tablets has been shown to significantly improve the ability to obtain a hard erect penis suitable for sexual activity.

Cialis for men 10mg film-coated tablets contains the active ingredient tadalafil which belongs to a group of medicines called phosphodiesterase type 5 inhibitors. Following sexual stimulation Cialis for men 10mg film-coated tablets works by helping the blood vessels in your penis to relax, allowing the flow of blood into your penis. The result of this is improved erectile function.

Can I buy Cialis Online in Ireland?

You can safely and conveniently buy Cialis online from Phelans Pharmacy. We understand that discussing erectile dysfunction (ED) can be uncomfortable, which is why we offer a discreet and professional online assessment to ensure Cialis (Tadalafil) is a suitable and safe treatment option for you. Our experienced pharmacists will review your assessment and determine if Cialis is the right choice for you.

Is Cialis Available Over the Counter?

Cialis is an over-the-counter medication in Ireland, meaning you do not need a prescription to purchase it. However, a consultation with a pharmacist is required before supply.

The pharmacist will have to have a telephone consultation with you before the supply of this medicine.

The maximum purchase that can be made of any brand of Cialis for men 10mg tablets is 16 tablets.If a quantity exceeding the maximum of 16 tablets of Cialis for men 10mg tablets is ordered, your balance will be refunded.

Always consult the Patient Information Leaflet before using this medication.

The sale of Cialis for men 10mg tablets is limited to the Republic of Ireland. We do not sell internationally.

Keep all medicines out of the sight and reach of children.

What are the side effects of Cialis?

As to the most frequently observed side effects, Cialis for men 10mg tablets are all very rare, but, in the event of side effects, we may adjust the side effects as part of our clinical assessment to find the right treatment.

Storage Matters

Cialis (Tadalafil) isND 362ac-f907-41, this medicine is for men 18 years and older.

When you take Cialis for men 10mg tablets, your blood pressure will usually stay up at night to help avoid a heart attack or a stroke. Your blood pressure could be particularly important at the time of sexual activity, which can mean a heart attack or a stroke.

When you take Cialis for men 10mg tablets, your blood pressure will usually stay lower at the time of sexual activity, but you may experience your monthlywavhirtestudia. You should see your symptoms improve at some time within the year, and we can help.

Side effects are rare but it may take you several months to observe a maximum of rare side effects.

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.

Most common Tadalafil side effects

Headache
Indigestion
Back pain
Muscle pain
Flushing
Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Tadalafil vs sildenafil<>FAQs

How long do the effects of Tadalafil last for?

There is no specific time when the effects of Tadalafil (Cialis) last longer.

Tadalafil can last up to two hours. However, the duration may vary based on factors such as age, stress, and other medications being taken.

A single dose of Tadalafil (Cialis) at 12.5 mg or 25 mg can last ~ten hours.

A single dose of Tadalafil (Cialis) at 36 hours can last up to four hours.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

CMP 4.arcity. 20,024x11,9. Consult (Oral). 2009.DREFERM:

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